Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals.

IMPORTANCE:

One approach to understanding the genetic complexity of schizophrenia is to study associated behavioral and biological phenotypes that may be more directly linked to genetic variation.

OBJECTIVE:

To identify single-nucleotide polymorphisms associated with general cognitive ability (g) in people with schizophrenia and control individuals.

JAMA psychiatry 71.6 (2014): 647-656.
Dickinson, Dwight, et al.
https://www.ncbi.nlm.nih.gov/pubmed/24718902