News & Events

Highlighted Events

Alex Nemiroff and Dr. Steven Petrou Presenting at Epilepsy Precision Medicine Conference

September 16-17, 2019, Washington, D.C.

RogCon Sponsoring The SCN2A Family and Professional Conference

August 1, 2019, Seattle, WA

Dr. Steven Petrou Presents Data on Antisense Oligonucleotide Development Program for SCN2A Epilepsy at 2019 World Orphan Drug Congress

April 10, 2019 Gaylord National Harbor Hotel, Oxon Hill, Maryland

AES Late-Breaking Abstract Presentation: Antisense oligonucleotide therapy for SCN2A gain-of-function epilepsies

December 1, 2018, Ernest N. Morial Convention Center, New Orleans, Louisiana

Press Releases

RogCon and Prometheus Research Enter into Partnership to Support International Natural History Study on SCN2A Mutations

January 14, 2019

RogCon Biosciences Launches with Late-Breaking Presentation on SCN2A Epilepsy at the 2018 AES Meeting

December 1, 2018

In The News

Antisense Oligonucleotide Therapy For SCN2A Gain-of-Function Epilepsies: AES 2018 Poster

December 1, 2018

Relationship of Electrophysiological Dysfunction and Clinical Severity in SCN2A-Related Epilepsies.

September 13, 2018

SCN2A mutation in an infant presenting with migrating focal seizures and infantile spasm responsive to a ketogenic diet.

September 1, 2018

Dominant SCN2A Mutation Causes Familial Episodic Ataxia and Impairment of Speech Development.

August 30, 2018

Nav1. 2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

July 19, 2018

The autism-associated gene Scn2a plays an essential role in synaptic stability and learning.

July 10, 2018

Progress in Understanding and Treating SCN2A-Mediated Disorders.

July 1, 2018

Dynamic action potential clamp predicts functional separation in mild familial and severe de novo forms of SCN2A epilepsy.

June 12, 2018

Diagnostic outcomes for genetic testing of 70 genes in 8565 patients with epilepsy and neurodevelopmental disorders.

April 14, 2018

FOXD3 inhibits SCN2A gene transcription in intractable epilepsy cell models.

April 1, 2018

Neurotransmitters and Sodium Channelopathies; Possible Link?

November 10, 2017

Opposing effects on NaV1. 2 function underlie differences between SCN2A variants observed in individuals with autism spectrum disorder or infantile seizures.

August 1, 2017

Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders.

May 1, 2017

Mutations of voltage-gated sodium channel genes SCN1A and SCN2A in epilepsy, intellectual disability, and autism.

October 10, 2016

Mutation screening of SCN2A in schizophrenia and identification of a novel loss-of-function mutation.

April 26, 2016

SCN2A encephalopathy A major cause of epilepsy of infancy with migrating focal seizures.

August 25, 2015

Beyond the Ion Channel: ILAE Genetics Commission Blog

August 11, 2015

Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals.

June 7, 2014